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Test Code FAPIX Apixaban, Plasma

Additional Codes

Epic# -

LAB000 (enter test name into comments)

 

Cerner name(s):

  • Miscellaneous Sendout


Specimen Required


***Must submit one specimen per order. Specimens cannot be shared between multiple orders.***

 

Collection Container/Tube: Lavender top or pink top (EDTA) (Plasma gel/PST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL Plasma

Collections Instructions:

1. Centrifuge and aliquot 2 mL of plasma into a plastic vial.

2. Send refrigerated.

Specimen Stability Information: Ambient 29 days/Refrigerated 29 days/Frozen (-20° C) 2 years


Secondary ID

75395

Method Name

High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Apixaban, Plasma

Specimen Type

Plasma EDTA

Specimen Minimum Volume

Plasma: 0.7 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma EDTA Refrigerated (preferred) 29 days
  Ambient  29 days
  Frozen 

Reject Due To

  All specimens will be evaluated by the processing and performing laboratories for test suitability.

Reference Values

Reporting limit determined each analysis.

 

Mean peak plasma concentrations of apixaban following a single oral administration of 5, 10, 25, or 50 mg oral tablets are as follows:

5 mg: 104.7 ng/mL (range: 79.7 to 129.7)

10 mg: 176.3 ng/mL (range: 134.3 to 218.3)

25 mg: 365.1 ng/mL (range: 348.1 to 382.1)

50 mg: 685.2 ng/mL (range: 663.2 to 707.2)

Interpretation

In a study of 1691 patients taking apixaban, doses ranging from 2.5 mg twice a day to 20 mg once a day, apixaban plasma concentrations ranged from 1 to 933 ng/mL, with a median value of 105 ng/mL.

Day(s) Performed

Monday through Sunday

Report Available

9 to 11 days

Performing Laboratory

NMS Labs
Memorial Hospital Belleville - Shiloh Note:

Specimen will be sent to Mayo who will forward to NMS Labs for testing.

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FAPIX Apixaban, Plasma 74218-9

 

Result ID Test Result Name Result LOINC Value
Z3530 Apixaban 74218-9

Test Classification

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the U.S. Food and Drug Administration.

Clinical Information

Refer to www.nmslabs.com/test-catalog