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Gentamicin (Random, Trough, Peak)

Additional Codes

Epic# -

PEAK - LAB28

RANDOM - LAB27

TROUGH - LAB26

 

Cerner name(s):

  • Gentamicin level peak
  • Gentamicin Pk
  • Gentamicin level random
  • Gentamicin Rnd
  • Gentamicin level tough
  • Gentamicin Tr

Performing Lab(s)

Memorial-Belleville only

Specimen Requirement (s)

Specimen Type: Plasma

Container/Tube:   mint green LiHep Tube (preffered)

Specimen Volume:  1 mL

Specimen Minimum Volume:  0.5 mL plasma

 

Collection Instructions:

  • Random - Specimen may be drawn at any time.
  • Trough - Collection time should be within 30 minutes before the next dose.
  • Peak - Collection time should be 30 minutes following IV dose or 60 minutes following IM injection.

Unacceptable Conditions

Avoid hemolysis. 

Day(s)/Shift(s) Test Set Up and Turnaround Time

Sunday through Saturday

Hours: 24 hours

 

Turnaround Time:

STAT: 60 minutes

Routine: less than 8 hours from receipt.

Transport and Stability

Transport temperature: Ambient to lab

 

Analyte Stability

Ambient: 8 hours

Refrigerated: 8 hours

Frozen: 2 weeks

Reference Values

Random

Age

Reference Values

Critical Low

Critical High

NA

None

None

 None

Trough

Age

Reference Values

Critical Low

Critical High

0 – 18 years

0 – 0.9 mcg/mL

None

≥ 2.1 mcg/mL

>18 years

0 – 2 mcg/mL

None

≥ 2.1 mcg/mL

 

Peak

Age

Reference Values

Critical Low

Critical High

0 – 18 years

8 - 12 mcg/mL

None

None

>18 years

3 - 10 mcg/mL

None

None

 

CPT/LOINC Codes

80170

Interpretive Data

Interpretive Data - Random

No reference ranges have been established for random drug levels.

Current Interpretive Data was last revised on 06/05/2021.

 

Interpretive Data - Peak

Greater than or equal to 18yrs:

Therapeutic Range:

UTI/GPC synergy: 3-5 mcg/mL

Systemic illness: 6-8 mcg/mL

Sepsis: 8-10 mcg/mL

GPC synergy refers to the synergistic effect of aminoglycosides with other antibiotics in treating infections caused by gram positive cocci (e.g. Enterococcus).

Current Interpretive Data was last revised on 06/05/2021.

 

Interpretive Data - Trough

Greater than or equal to 18yrs:

Therapeutic Range:

UTI/GPC synergy: 0-1 mcg/mL

Systemic illness: 0-1 mcg/mL

Sepsis: 0-2 mcg/mL

GPC synergy refers to the synergistic effect of aminoglycosides with other antibiotics in treating

infections caused by gram positive cocci (e.g. Enterococcus).

Current Interpretive Data was last revised on 06/05/2021.