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HelpTobramycin (Peak, Trough, Random) Level
Performing Lab(s)
Memorial-Belleville only
Specimen Requirement (s)
Specimen: plasma
Type: Container/Tube: Mint green (LiHep) tubes
Specimen Volume: 2 mL each
Specimen Minimum Volume: 1 mL of plasma
Collection instructions:
- Peak level
- IV infusion - Collect 30 minutes following completion of infusion.
- IM infusion - Collect 60 minutes following completion of infusion.
- Trough level
- Collect not more than 30 minutes before next dose.
- Random - Collect at any time.
Lab instructions: NA
Day(s)/Shift(s) Test Set Up and Turnaround Time
Sunday through Saturday
Hours: 24 hours
Turnaround Time:
STAT: 60 minutes
Routine: less than 8 hours from receipt
Transport and Stability
Transport temperature: Ambient to lab
CPT/LOINC Codes
80200
Reference Values - Interpretive Data
Tobramycin, Peak
|
Age |
Reference Values |
|
0 – 18 years |
8.0 - 12.0 mcg/mL |
|
>18 years |
3.0 – 10.0 mcg/mL |
Interpretive Data (Peak)
Therapeutic Range: ≥18 years
UTI: 3-5 µg/mL
Systemic Illness: 6-8 µg/mL
Sepsis: 8-10 µg/mL
Tobramycin, Trough
|
Age |
Reference Values |
Critical High |
|
0 – 18 years |
< 0.9 mcg/mL |
> 2.0 mcg/mL |
|
>18 years |
< 2.0 mcg/mL |
> 2.0 mcg/mL |
Interpretive Data (trough):
Therapeutic Range: ≥18 years
UTI: 0-1 µg/mL
Systemic Illness: 0-1 µg/mL
Sepsis: 0-2 µg/mL
Tobramycin, Random
No reference ranges established for random specimens.